Antitumor Steroids by R T Blickenstaff

By R T Blickenstaff

Antitumor Steroids examines using steroids, besides nonsteroidal antiestrogens and a few benzo[a]carbazoles, within the remedy of melanoma. It explains the mechanism during which steroids and their receptors interact to impact their physiological services typically and their antitumor job particularly. It additionally describes the systematic screening of antitumor compounds remoted from traditional assets.
Organized into 9 chapters, this booklet starts with an outline of the position of steroids in melanoma therapy. It then discusses the estrogens, antiestrogens, and compounds (all containing an fragrant A-ring). the following chapters ponder androgens, a few antiandrogens, derivatives in response to C-19 steroids, progestins and corticoids, bile acids, and compounds with a side-chain carboxyl crew. The e-book explains the biogenesis and metabolism of androgens; the pharmacology of medroxyprogesterone acetate; the antitumor homes of evidently taking place corticosteroids; sterols and cucurbitacins; nutrition D and its metabolites; and cardenolides, bufadienolides, and withanolides. The ebook concludes with a bankruptcy on bile acids, sapogenins and its analogs, and miscellaneous steroids.
This booklet is a important source for natural and medicinal chemists biochemists, and pharmacologists attracted to using steroids in treating cancer.

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